NOC:Principles and Applications of NMR Spectroscopy

Lecture 1 - Introduction to NMR spectroscopy

Lecture 2 - The alignment of nuclear spins in presence of magnetic field

Lecture 3 - Introduction to rotating frame

Lecture 4 - Free induction decay and Fourier transformation of FID

Lecture 5 - NMR Hardware

Lecture 6 - The concept of chemical shift

Lecture 7 - Factors that affect chemical shifts

Lecture 8 - Chemical shift referencing

Lecture 9 - J-coupling

Lecture 10 - Recap of basics

Lecture 11 - Introduction to general one dimensional NMR experiment

Lecture 12 - Practical aspects of recording a 1D NMR experiment - I

Lecture 13 - Practical aspects of recording a 1D NMR experiment - II

Lecture 14 - Practical aspects of recording a 1D NMR experiment - III

Lecture 15 - NMR Data processing

Lecture 16 - Basic aspects of 1D proton NMR analysis

Lecture 17 - Analysis of an example 1D proton spectrum

Lecture 18 - Analysis of 1D 1H NMR spectra of molecules - I

Lecture 19 - Analysis of 1D 1H NMR spectra of molecules - II

Lecture 20 - 1D 13C NMR

Lecture 21 - Why do we need 2D NMR

Lecture 22 - A qualitative explanation of how 2D NMR experiment works

Lecture 23 - Principles of 2D COSY and Total correlation spectroscopy (2D TOCSY)

Lecture 24 - 2D NOE-spectroscopy

Lecture 25 - 2D NOESY and 2D ROESY

Lecture 26 - What is heteronuclear correlation NMR spectroscopy

Lecture 27 - Sensitivity enhancement of heternuclei via polarization transfer

Lecture 28 - Heteronucler multiple quantum NMR spectroscopy (2D HMQC) and Heteronuclear single quantum NMR spectroscopy (2D HSQC)

Lecture 29 - Practical aspects of recording and processing 2D HMQC or HSQC

Lecture 30 - HMBC and its utility

Lecture 31 - 2D HSQC TOCSY and its analysis with examples

Lecture 32 - Structure determination of molecules by NMR

Lecture 33 - Structure determination of peptides - I

Lecture 34 - Structure determination of peptides - II

Lecture 35 - Structure determination of peptides - III

Lecture 36 - Chemical exchange

Lecture 37 - Hydrogen or deuterium exchange

Lecture 38 - Diffusion ordered spectroscopy DOSY I

Lecture 39 - DOSY II

Lecture 40 - STD NMR for drug target interactions